In this paper, based on exponentially distributed trap density of states (DOS) for grain boundary, a solution to effective mobility (μeff) is derived. Within the model, an effective width of grain boundary (GB) depletion region (LGB.eff) and drain induced grain barrier lowering effect on GB barrier height (ψB), is considered. The μeff model is then verified with μeff extracted from simulation. To this end, a computer aided design simulation is calibrated against the experimental data and μeff is then calculated from the simulated channel current. The μeff model is compared with calculated μeff to validate the model and a good agreement between them is achieved. In addition, we also investigate the dependence of μeff on GB DOS parameters and device temperature. The same validation process is also performed at various GB locations and angles to analyze the effect of GB shape on μeff.